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The analytical data includes NMR raw data and HRMS, IR and SFC data as PDF files.\n\nAll amphipathic compounds were constructed to be mimics of antimicrobial peptides (AMPs) and were tested for their antimicrobial activity in the study \"Investigation of Tetrasubstituted Heterocycles Reveals Hydantoins as a Promising Scaffold for Development of Novel Antimicrobials with Membranolytic Properties\". The structure of all compounds can be found in the data files."},"dsDescriptionDate":{"typeName":"dsDescriptionDate","multiple":false,"typeClass":"primitive","value":"2022-11-14"}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Chemistry","Medicine, Health and Life Sciences"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Antimicrobial peptides"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"AMPs"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Amphipathic, Tetrasubstituted Barbiturates"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Small mimics of antimicrobial peptides"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"SMAMPs"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Nuclear magnetic resonance"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"NMR"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"High resolution mass spectrometry"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"HRMS"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Infrafred spectroscopy"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"IR"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Supercritical fluid chromatography"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"SFC"}}]},{"typeName":"publication","multiple":true,"typeClass":"compound","value":[{"publicationCitation":{"typeName":"publicationCitation","multiple":false,"typeClass":"primitive","value":"Manuel K. Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug, Klara Stensvåg, Morten B. Strøm, Annette Bayer, Investigation of tetrasubstituted heterocycles reveals hydantoins as a promising scaffold for development of novel antimicrobials with membranolytic properties, Eur. J. Med. 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