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Persistent Identifier
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doi:10.18710/T77K01 |
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Publication Date
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2021-05-06 |
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Title
| Mouse liver sinusoidal endothelial cell responses to the glucocorticoid receptor agonist dexamethasone in vitro |
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Author
| Bhandari, SabinUiT The Arctic University of NorwayORCID0000-0003-3837-027X |
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Point of Contact
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Sørensen, Karen Kristine (UiT The Arctic University of Norway) |
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Description
| The data represents C57Bl/6 mouse LSEC proteome at different timepoints (1h, 10h, and 48h) post seeding in the presence or absence of 1micromolar dexamethasone to elucidate time dependent, and dexamethasone specific changes in LSEC responses, generated using a tandem mass tag (TMT)6-plex strategy on a highly sensitive Orbitrap Fusion Lumos mass spectrometer and the SPS MS3 method. (2021-04-26) |
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Subject
| Medicine, Health and Life Sciences |
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Keyword
| Endothelial cell (MeSH) https://www.ncbi.nlm.nih.gov/mesh/68042783
Proteomics (MeSH) https://www.ncbi.nlm.nih.gov/mesh/?term=Proteomics
Proteome (MeSH) https://www.ncbi.nlm.nih.gov/mesh/?term=Proteome
Cell Survival (MeSH) https://www.ncbi.nlm.nih.gov/mesh/68002470
Endocytosis (MeSH) https://www.ncbi.nlm.nih.gov/mesh/68004705
Receptors, Scavenger (MeSH) https://www.ncbi.nlm.nih.gov/mesh/?term=Receptors%2CScavenger |
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Related Publication
| Is Supplement To: Bhandari S, Kyrrestad I, Simón-Santamaría J, Li R, Szafranska KJ, Dumitriu G, Sánchez Romano J, Smedsrød B and Sørensen KK (2024) Mouse liver sinusoidal endothelial cell responses to the glucocorticoid receptor agonist dexamethasone. Front. Pharmacol. 15:1377136. doi: 10.3389/fphar.2024.1377136 doi 10.3389/fphar.2024.1377136 https://doi.org/10.3389/fphar.2024.1377136 |
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Language
| English |
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Producer
| UiT The Arctic University of Norway (UiT) https://en.uit.no/ |
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Production Date
| 2019-03-30 |
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Production Location
| Proteomics and Metabolomics Core Facility (PRiME), UiT The Arctic University of Norway |
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Contributor
| Data Curator: Brunn, Jack-Ansgar
Data Curator: Bhandari, Sabin
Hosting Institution: UiT The Arctic University of Norway
Project Leader: Sørensen, Karen
Project Member: Li, Ruomei
Project Member: Kyrrestad, Ingelin
Project Manager: Smedsrød, Bård
Project Member: Simon-Santamaria, Jaione
Research Group: Vascular Biology Research Group (VBRG)
Funder: UiT The Arctic University of Norway |
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Funding Information
| The Research Council of Norway: 262538 |
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Distributor
| UiT The Arctic University of Norway (UiT The Arctic University of Norway) https://dataverse.no/dataverse/uit |
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Distribution Date
| 2024-11-02 |
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Depositor
| Bhandari, Sabin |
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Deposit Date
| 2021-04-26 |
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Date of Collection
| Start Date: 2019-03-30; End Date: 2019-05-30 |
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Data Type
| Experimental data |
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Software
| MaxQuant, Version: 1.6.10
Perseus, Version: 1.6.14.0 |
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Related Dataset
| The original datasets are deposited in the ProteomeXchange repository, accession number PXD041381. The data is available at: https://proteomecentral.proteomexchange.org/ui?search=PXD041381 |